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Generic Duphaston (Dydrogesterone)
Duphaston is a synthetic hormone applied in treatment of secondary amenorrhoea, dysfunctional uterine bleeding and post-menopausal symptoms.
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10mg
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Duphaston $92.00
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10mg
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Duphaston $118.00
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10mg
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Duphaston $187.00
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10mg
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Duphaston $253.00
$210.99
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10mg
120pills
Duphaston $304.00
$252.99
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Common use

Duphaston contains dydrogesterone, a synthetic hormone similar to progesterone. The medication is used to restore the hormone balance when synthesis of progesterone in the body is not sufficient (sterility, abortion, premenstrual syndrome, dysmenorrhea, irregular menstruation, secondary amenorrhea, dysfunctional uterine bleeding). The medication stimulates beginning of the secretory phase in the endometrium thereby reducing the risk of endometrial hyperplasia and carcinogenesis, which increases due to estrogen.



Dosage and direction

Each condition requires special treatment and dose schedule. Follow all instructions of your doctor. To treat endometriosis take 10 mg of Duphaston two or three times a day from 5th to 25th day of your cycle. To treat infertility take 10 mg a day from 14th to 25th day of your cycle. The treatment should be done continuously for three, six and more following cycles. Contact your doctor about all details.



Precautions

Inform your doctor if you are pregnant or breastfeeding before to take this medication. Hormone replacement therapy should not be administered without a general medical examination, including pelvic examination. Your doctor may ask you to make mammogram examination regularly.



Contraindications

This medication cannot be used in individuals with hypersensitivity to Duphaston, Dubin-Johnson syndrome (an increase of conjugated bilirubin without elevation of liver enzymes), Rotor syndrome (a benign autosomal recessive bilirubin disorder).



Side effects

The most frequent adverse reactions include headache, nausea, dizziness, bloating, skin reactions (rash and itching), breast tenderness, menstrual spotting between periods



Drug interaction

Inductors of microsomal liver enzymes such as phenobarbital may accelerate the metabolism of Duphaston and weaken its effect.



Missed dose

If you forgot to take a dose contact your doctor about necessary actions.



Overdose

There is not information about possible overdose. Seek immediate medical help if you suspect overdose.



Storage

Store at room temperature between 20-25 C (68-77 F). Store away from moisture, heat, and sunlight. It is not recommended to store in a bathroom and places available for children.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

How does Vardenafil work and what pharmaceutical group does it belong to?

Erection of the penis is a haemodynamic process that is based on the relaxation of the cavernous body's smooth muscles and its arterioles. During sexual stimulation nitrogen oxide is released from the cavernous body's nerve ends and activates the enzyme cGMP. This results in relaxation of the smooth muscles in the cavernous body and increases blood flow to the penis. Vardenafil works by blocking PDE type 5(phosphodiesterase type 5) that is responsible for the inactivation of cGMP. This in its turn increases the amount of cGMP and improves erection.

Which conditions are treated with Vardenafil ?

Vardenafil is indicated for the treatment of erectile dysfunction manifested in inability to achieve and maintain erection, enough for the sexual intercourse.

What should a patient know prior to taking the medication?

  • Vardenafil should not be taken in known hypersensitivity or allergy to any of the medication ingredients.
  • Vardenafil is not intended to treat children and adolescents under 18 years of age.
  • Vardenafil should be used with caution in prolonged QT interval, anatomical deformation of the penis, priapism, blood diseases, severe liver and kidney diseases, arterial hypotension, recent heart attacks and strokes, tendency to bleedings, aggravation of stomach ulcers, aortal stenosis, idiopathic hypertrophic
  • Vardenafil is indicated only for men and should not be used by women.

Which adverse effects may manifest when using the medication?

The side effects of Vardenafil include: headache, hot flushing, dyspepsia, upset stomach, rhinitis, flu-like symptoms, increased levels of creatine kinase in the blood, nausea, dizziness, back pain.

In rare cases Vardenafil may cause arthritis, diarrhea, insomnia, muscle pain, blurred vision and others.

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Vardenafil?

The drug is affected by the following:

  • Alpha blockers
  • Heart arrhythmia medicines
  • Certain antibiotics
  • Grapefruit juice
  • Nitrates
  • Protease inhibitors

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient:

Vardenafil is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.