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Malegra DXT (Sildenafil/Duloxetine)
Malegra DXT is a combination drug, having both Sildenafil and Duloxetine in its compound. Malegra DXT provides its patient with longer sex before ejaculation, treating premature ejaculation problems.
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Common use

Malegra DXT is a combination drug, having both Sildenafil and Duloxetine in its compound. The therapeutic effect is great: aside from long and stable erection, usual for Sildenafil drugs, Malegra DXT provides its patient with longer sex before ejaculation, treating premature ejaculation problems.



Dosage and direction

Malegra DXT pill contains 100 mg of Sildenafil + 30 mg of Duloxetine, so the overall dose of active substances is 130 mg per tablet. The recommended dose is just one tablet of Malegra DXT at least an hour before planned sexual activity. The effect of the drug lasts for 6 hours and more, making your sexual experience rich and pleasant.



Precautions

Malegra DXT is not recommended to men younger than 18 years or older than 60 years old for possible complications. If you take Malegra DXT, you shouldn’t chew the tablet, but swallow it wholly. The drug does not protect the user from sexually transmitted diseases or AIDS. It’s dangerous to mix Malegra DXT with alcohol.



Contraindications

Cardiovascular diseases, blood pressure issues and liver problems make the use of Malegra DXT dangerous for health. Please, don’t use Sildenafil + Duloxetine combination in case you have any of those problems without a proper consultation with your doctor.



Possible side effect

Though Malegra DXT is commonly safe and causes minor to none adverse effects, you should take care using it. The best option is to consult your doctor for proper administration of the drug and a medical advice on its use. However, sometimes patients experience headaches, back pain, flushing and indigestion after they take the drug.



Drug interaction

Malegra DXT has the same interactions as Sildenafil + Duloxetine. Erythromycin and cimetidine cause the effect of Malegra DXT last longer, which is not useful. Taking the drug together with other alpha blockers, you expose yourself to a risk of low blood pressure.



Missed dose

You shouldn’t worry about a missed dose of Malegra DXT, because it’s a single-time action medication. You don’t have to take the drug regularly: you can only use it when you need its effect.



Overdose

Don’t overdose Malegra DXT! The maximum positive effect of the drug is achieved with just one tablet. Further increase in dose can lead to low blood pressure and other complications. If you feel dizziness, drowsiness or weakness after taking Malegra DXT, consult your medical care specialist on the further use of the drug.



Storage

Keep Malegra DXT blister in a dark dry place at room temperature.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

How does Vardenafil work and what pharmaceutical group does it belong to?

Erection of the penis is a haemodynamic process that is based on the relaxation of the cavernous body's smooth muscles and its arterioles. During sexual stimulation nitrogen oxide is released from the cavernous body's nerve ends and activates the enzyme cGMP. This results in relaxation of the smooth muscles in the cavernous body and increases blood flow to the penis. Vardenafil works by blocking PDE type 5(phosphodiesterase type 5) that is responsible for the inactivation of cGMP. This in its turn increases the amount of cGMP and improves erection.

Which conditions are treated with Vardenafil ?

Vardenafil is indicated for the treatment of erectile dysfunction manifested in inability to achieve and maintain erection, enough for the sexual intercourse.

What should a patient know prior to taking the medication?

  • Vardenafil should not be taken in known hypersensitivity or allergy to any of the medication ingredients.
  • Vardenafil is not intended to treat children and adolescents under 18 years of age.
  • Vardenafil should be used with caution in prolonged QT interval, anatomical deformation of the penis, priapism, blood diseases, severe liver and kidney diseases, arterial hypotension, recent heart attacks and strokes, tendency to bleedings, aggravation of stomach ulcers, aortal stenosis, idiopathic hypertrophic
  • Vardenafil is indicated only for men and should not be used by women.

Which adverse effects may manifest when using the medication?

The side effects of Vardenafil include: headache, hot flushing, dyspepsia, upset stomach, rhinitis, flu-like symptoms, increased levels of creatine kinase in the blood, nausea, dizziness, back pain.

In rare cases Vardenafil may cause arthritis, diarrhea, insomnia, muscle pain, blurred vision and others.

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Vardenafil?

The drug is affected by the following:

  • Alpha blockers
  • Heart arrhythmia medicines
  • Certain antibiotics
  • Grapefruit juice
  • Nitrates
  • Protease inhibitors

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient:

Vardenafil is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.