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Levitra24hrs
Generic Motilium (Domperidone)
Motilium improves upper gastrointestinal motility disordered in patients with chronic and sub-acute gastritis and diabetic gastroparesis.
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10mg
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10mg
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Common use

Motilium blocks pereferal and central dophamin receptors, removes inhibiting influence of dophamin on motor activity of gastrointestinal tract and increases evacuative and tone of stomach. It has anti-vomiting effect, soothes hiccup and nausea. Motilium is used to treat vomiting of different origin, hiccup, atonic gastrointestinal tract, necessity to accelerate peristalsis for X-ray examination, dispepsia caused by slow stomach, gastroesophageal reflux disease, esophagitis, gas, heartburn with or without passage of gastric contents into the mouth.



Dosage and directions

Take Motilium orally 30 minutes before a meal. In adults and children older than 5 y.o. take 10 mg 3-4 times a day when dispepsia is diagnosed. In patients with severe nausea and vomiting Motilium daily dose is 20 mg 3-4 times a day. In patients with kidney failure correction of the dose is necessary, number of daily intakes should not exceed 1-2 times. This is only general recommendations and for each individual case consult your doctor as different conditions require different correction of the dose.



Precautions

If you are pregnant or think you might be pregnant first consult your doctor or pharmacist before taking Motilium or any other medicine. Do not take Motilium if you are breast-feeding.



Contraindications

Hypersensitivity, bleeding in gastrointestinal tract, mechanical intestinal obstruction, perforation of the stomach or intestines, prolactinoma, infancy (younger than 5 y. o. and ones whose weight is less than 20 kg). Caution should be experienced in patients with renal / hepatic insufficiency, during lactation, pregnancy.



Possible side effect

Among most common side effects these can occur: transient spasms of the intestine, allergic reactions (skin rash, urticaria), hyperprolactinaemia (galactorrhoea, gynecomastia).



Drug interaction

Cimetidine and sodium bicarbonate reduce effects of Domperidone. Anticholinergic medications neutralize effect of Motilium. Blood levels of Motilium are increased by azole antifungal agents, macrolide antibiotics, HIV protease inhibitors, nefazodone (antidepressant). Motilium is compatible with antipsychotic (neuroleptics) medications, dopamine receptor agonists (bromocriptine, L-dopa). Simultaneous treatment with paracetamol and digoxin had no effect on the concentration of these medications in the blood.



Missed dose

If you missed a dose take it the soonest. If it is almost time of your next dose just skip it and return to your regular dosage schedule.



Overdose

Symptoms of overdose may include drowsiness, disorientation, extrapyramidal disorder (especially in children). If you think that took too much of Motilium and experience symptoms listed above contact your doctor immediately, you may need a medical help.



Storage

Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

How does Vardenafil work and what pharmaceutical group does it belong to?

Erection of the penis is a haemodynamic process that is based on the relaxation of the cavernous body's smooth muscles and its arterioles. During sexual stimulation nitrogen oxide is released from the cavernous body's nerve ends and activates the enzyme cGMP. This results in relaxation of the smooth muscles in the cavernous body and increases blood flow to the penis. Vardenafil works by blocking PDE type 5(phosphodiesterase type 5) that is responsible for the inactivation of cGMP. This in its turn increases the amount of cGMP and improves erection.

Which conditions are treated with Vardenafil ?

Vardenafil is indicated for the treatment of erectile dysfunction manifested in inability to achieve and maintain erection, enough for the sexual intercourse.

What should a patient know prior to taking the medication?

  • Vardenafil should not be taken in known hypersensitivity or allergy to any of the medication ingredients.
  • Vardenafil is not intended to treat children and adolescents under 18 years of age.
  • Vardenafil should be used with caution in prolonged QT interval, anatomical deformation of the penis, priapism, blood diseases, severe liver and kidney diseases, arterial hypotension, recent heart attacks and strokes, tendency to bleedings, aggravation of stomach ulcers, aortal stenosis, idiopathic hypertrophic
  • Vardenafil is indicated only for men and should not be used by women.

Which adverse effects may manifest when using the medication?

The side effects of Vardenafil include: headache, hot flushing, dyspepsia, upset stomach, rhinitis, flu-like symptoms, increased levels of creatine kinase in the blood, nausea, dizziness, back pain.

In rare cases Vardenafil may cause arthritis, diarrhea, insomnia, muscle pain, blurred vision and others.

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Vardenafil?

The drug is affected by the following:

  • Alpha blockers
  • Heart arrhythmia medicines
  • Certain antibiotics
  • Grapefruit juice
  • Nitrates
  • Protease inhibitors

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient:

Vardenafil is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.