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Levitra24hrs
Generic Rulide (Roxithromycin)
Rulide is a macrolide antibiotic used to treat infections of of upper respiratory tract.
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Common use

Rulide is a semi-synthetic macrolide antibiotic used for the treatment of mild to moderate infections of upper respiratory tract infections (acute pharyngitis, tonsillitis, sinusitis) caused by susceptible pathogens. Rulide prevents bacteria from growing, by inhibiting their protein synthesis.



Dosage and directions

Rulide is taken once or twice daily, a daily dose is 300 mg for adults.Usual course of treatment is 7-10 days.



Precautions

In patients with hepatic failure half-life of Rulide in serum increases. If liver disorders are severe (hepatic cirrhosis with jaundice and/or ascites), the dose of the medications should be corrected.

Small amounts of Rulide are excreted in human breast milk so breast feeding or treatment of the mother should be stopped if required.



Contraindications

Hypersensitivity to Rulide or macrolide antibiotics, concomitant therapy with vasoconstrictive ergotamine type medications.



Possible side effect

Most common side effects are: nausea, vomiting, diarrhea, epigastric pain, flatulence, headache, dizziness, malaises, hives, rash, swelling of tongue and face, moniliasis (candidiasis)



Drug interaction

Rulide is able to increase plasma levels of theophylline when co-administered. It also may affect activity of warfarin and erythromycin.



Missed dose

If you missed a dose take it as soon as you remember. If it almost time of your next dose just skip it and return to your regular schedule. Never double dose this medication.



Overdose

In case of serious and persistent symptoms of allergy (hives, swelling of face and tongue, rash) consult your doctor about medical attention. In general Rulide is well tolerated.



Storage

Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets. Do not use after expiration term.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment

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Erection of the penis is a haemodynamic process that is based on the relaxation of the cavernous body's smooth muscles and its arterioles. During sexual stimulation nitrogen oxide is released from the cavernous body's nerve ends and activates the enzyme cGMP. This results in relaxation of the smooth muscles in the cavernous body and increases blood flow to the penis. Vardenafil works by blocking PDE type 5(phosphodiesterase type 5) that is responsible for the inactivation of cGMP. This in its turn increases the amount of cGMP and improves erection.

Which conditions are treated with Vardenafil ?

Vardenafil is indicated for the treatment of erectile dysfunction manifested in inability to achieve and maintain erection, enough for the sexual intercourse.

What should a patient know prior to taking the medication?

  • Vardenafil should not be taken in known hypersensitivity or allergy to any of the medication ingredients.
  • Vardenafil is not intended to treat children and adolescents under 18 years of age.
  • Vardenafil should be used with caution in prolonged QT interval, anatomical deformation of the penis, priapism, blood diseases, severe liver and kidney diseases, arterial hypotension, recent heart attacks and strokes, tendency to bleedings, aggravation of stomach ulcers, aortal stenosis, idiopathic hypertrophic
  • Vardenafil is indicated only for men and should not be used by women.

Which adverse effects may manifest when using the medication?

The side effects of Vardenafil include: headache, hot flushing, dyspepsia, upset stomach, rhinitis, flu-like symptoms, increased levels of creatine kinase in the blood, nausea, dizziness, back pain.

In rare cases Vardenafil may cause arthritis, diarrhea, insomnia, muscle pain, blurred vision and others.

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Vardenafil?

The drug is affected by the following:

  • Alpha blockers
  • Heart arrhythmia medicines
  • Certain antibiotics
  • Grapefruit juice
  • Nitrates
  • Protease inhibitors

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient:

Vardenafil is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.