Erection of the penis is a haemodynamic process that is based on the relaxation of the cavernous body's smooth muscles and its arterioles. During sexual stimulation nitrogen oxide is released from the cavernous body's nerve ends and activates the enzyme cGMP. This results in relaxation of the smooth muscles in the cavernous body and increases blood flow to the penis. Vardenafil works by blocking PDE type 5(phosphodiesterase type 5) that is responsible for the inactivation of cGMP. This in its turn increases the amount of cGMP and improves erection.
Vardenafil is indicated for the treatment of erectile dysfunction manifested in inability to achieve and maintain erection, enough for the sexual intercourse.
The side effects of Vardenafil include: headache, hot flushing, dyspepsia, upset stomach, rhinitis, flu-like symptoms, increased levels of creatine kinase in the blood, nausea, dizziness, back pain.
In rare cases Vardenafil may cause arthritis, diarrhea, insomnia, muscle pain, blurred vision and others.
It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.
The drug is affected by the following:
Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.
Vardenafil is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.